Ticlopidine, a new anti-thrombotic drug.

indirect immunofluorescent test for Lyme disease (Institut Pasteur, Paris), Rose Bengal Plate test, immunoelectrophoresis and IgG secretion index. After the last episode electrophysiological studies (motor conduction velocity and F wave latency in the legs, brainstem auditory evoked responses, visual evoked responses) and a cerebral and whole spinal cord MRI scans were all normal. Our patient had recurrent meningomyelitis and latterly encephalitis, in which each episode was preceded by fever and myalgia and developing severe neurological deficits requiring, on one occasion, mechanical ventilation. In spite of the severity of the motor and sensory dysfunction there was always complete recovery. The initial CSF inflammatory profile was the only abnormality found. All the other repeated investigations were normal or negative. We can only find one similar report in the literature.' LUIS M MONTEIRO MANUEL CORREIA Neurological Service, Hospital Geral de Santo Ant6nio, 4000 Oporto, Portugal